CD7 (T-Cell Leukemia Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD7 (T-Cell Leukemia Marker) |
| Clone | [B-F12] |
| Host Species | Mouse |
| Reactive Species | human, porcine, guinea pig. |
| Isotype | IgG2a, kappa |
| Format | unconjugated |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes a protein of 40kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 ass |
| Immunogen | Immunogen: Chronic Lymphoid Leukemia cells (CLL) |
| Other Names | [GP40; Leu9; p41; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41], [CD7; CD7; GP40; TP41; Tp40; LEU-9] |
| Gene, Accession # | [CD7], Gene ID: 924, NCBI: NP_006128.1, UniProt: P09564 |
| Catalog # | MBS438882 |
| Price | $190, $340, $340 |
| Order / More Info | CD7 (T-Cell Leukemia Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Knapp W et al. eds. Leukocyte typing IV, p341, Oxford University Press, Oxford, 1989.2. Miwa H, et al biological characteristics of CD7( ) acute leukemia. Leuk Lymphoma. 1996;21:239-44. 3. Rabinowich H, et al. J. Immunol. 1994 153(8):3504-3513.4. Emara M, et al. A human suppressor T-cell factor that inhibits T-cell replication by interaction with the IgM-Fc receptor (CD7). Hum Immunol. 1989;25(2):87-102.5. Thurlow PJ, A monoclonal antibody detecting a new human T cell antigen, HuLy-m2. Transplantation 1984, 38(2):143-147.6. Saxena A, et al. Biologic and clinical significance of CD7 expression in acute myeloid leukemia. Am J Hematol. 1998;58(4):278-84 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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