SQSTM1 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | SQSTM1 |
| Clone | [1336CT763.152.125] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1,kappa |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This SQSTM1 antibody is generated from mice immunized with a recombinant protein. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures). Links ALIS to the autophagic machinery via direct interaction with MAP1 LC3 family members. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. |
| Immunogen | n/a |
| Other Names | [Sequestosome-1; EBI3-associated protein of 60 kDa; EBIAP; p60; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; Ubiquitin-binding protein p62; SQSTM1; ORCA; OSIL] |
| Gene, Accession # | [SQSTM1], Gene ID: 8878, NCBI: NP_001135770.1, UniProt: Q13501 |
| Catalog # | MBS9200590 |
| Price | $165, $370 |
| Order / More Info | SQSTM1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Devergne O.,et al.J. Virol. 70:1143-1153(1996). Joung I.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:5991-5995(1996). Ota T.,et al.Nat. Genet. 36:40-45(2004). Schmutz J.,et al.Nature 431:268-274(2004). Vadlamudi R.K.,et al.FEBS Lett. 435:138-142(1998). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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