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Antigenic Specificity | Sulfotransferase family 1E, estrogen-preferring, member 1 |
Clone | [CPTC-SULT1E1-1] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG2b |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunohistology (Formalin-Fixed) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis. |
Immunogen | Immunogen: Recombinant full-length human SULT1E1 protein Positive Control: HEP G2, liver, intestine and kidney. |
Other Names | [EST; EST-1; EST1; Estrogen sulfotransferase; estrogen-preferring; estrone sulfotransferase; ST1E1; STE; Sulfotransferase 1E1; Sulfotransferase; Sulfotransferase estrogen preferring] |
Gene, Accession # | [SULT1E1], Gene ID: 6783, NCBI: NP_005411.1, UniProt: P49888 |
Catalog # | MBS4380700 |
Price | $190, $340, $340 |
Order / More Info | Sulfotransferase family 1E, estrogen-preferring, member 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Rebbeck, T.R., et al. 2006. J. Natl. Cancer Inst. 98: 1311-1320.; Allali-Hassani, A., et al. 2007. PLoS Biol. 5: e97. |