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Antigenic Specificity | Human Osteopontin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | purified |
Size | 0.1 mL |
Concentration | 1ug/ul |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antiserum is directed against human osteopontin. The antibody recognizes the full-length osteopontin protein (which runs at 66 kD on westerns), as well as the C-terminal fragments of both thrombin and MMP-cleaved OPN. The 32 kD MMP-cleaved C-fragment is recognized, but not the 40 kD N-terminal fragment. Cross reactivity occurs with osteopontin from swine and dog. Reactivity with osteopontin from other sources has not been determined. Osteopontin (OPN) is an arginine-glycineaspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. OPN is multifunctional, with activities in cell migration, cell survival, inhibition of calcification, regulation of immune cell function, and control of tumor cell |
Immunogen | Immunogen: This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide C-K-S-K-K-F-R-R-P-D-I-Q-YP-D corresponding to human osteopontin proteins conjugated to KLH using maleimide. A residue of cysteine was added to the amino terminal end to facilitate coupling. |
Other Names | [osteopontin; osteopontin; secreted phosphoprotein 1] |
Gene, Accession # | Gene ID: 6696 |
Catalog # | MBS4156682 |
Price | $540 |
Order / More Info | Human Osteopontin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |