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Antigenic Specificity | Aldo-keto Reductase Family 1 Member B1 (Adrenal Marker) |
Clone | [CPTC-AKR1B1-3] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG1 |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistology (Formalin-Fixed) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: AKR1B1, also deisgnated as aldose reductase, is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. It has also been shown to have decreased expression in adrenocortical cancer, and possibly play a role in adrenal tumorigenesis. It has been suggested that AKR1B1 could be investigated as a marker of malignancy for adrenal tumor diagnosis. |
Immunogen | Immunogen: Recombinant human full-length AKR1B1protein Positive Control: 293T, A431, HeLa, HepG2, MOLT4 and Raji whole cell lysates; HeLa cells; Human colon carcinoma tissue. |
Other Names | [AKR1B1; Aldehyde reductase; aldehyde reductase 1; Aldo-keto reductase family 1 member B1; aldo-keto reductase family 1, member B1 (aldose reductase); Aldose reductase; AR; Lii5-2 CTCL tumor antigen; low Km aldose reductase] |
Gene, Accession # | [AKR1B1], Gene ID: 231, NCBI: NP_001619.1, UniProt: P15121 |
Catalog # | MBS4380555 |
Price | $190, $340, $340 |
Order / More Info | Aldo-keto Reductase Family 1 Member B1 (Adrenal Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Bohren, K.M., et al. J. Biol. Chem. 264: 9547-9551.; LefrancI ois-Martinez, Anne-Marie, et al. OUP Academic, Oxford University Press. |