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Antigenic Specificity | MMP12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. The gene is part of a cluster of MMP genes whic |
Immunogen | Immunogen: Recombinant protein of human MMP12 |
Other Names | [ME; HME; MME; MMP-12] |
Gene, Accession # | [MMP12], Gene ID: 4321, NCBI: NP_002417.2, UniProt: P39900 |
Catalog # | MBS9129696 |
Price | $275, $430 |
Order / More Info | MMP12 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |