Bim BH3 Domain, 130-165 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Bim BH3 Domain, 130-165 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Bim BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-165 amino acids from human Bim BH3 Domain. Bim belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bim contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte |
| Immunogen | n/a |
| Other Names | [Bcl-2-like protein 11; Bcl2-L-11; Bcl2-interacting mediator of cell death; BCL2L11; BIM] |
| Gene, Accession # | [BCL2L11], Gene ID: 10018, NCBI: NP_001191035.1, UniProt: O43521 |
| Catalog # | MBS9206947 |
| Price | $165, $370 |
| Order / More Info | Bim BH3 Domain, 130-165 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Chen, D., et al., Proc. Natl. Acad. Sci. U.S.A. 101(5):1235-1240 (2004). Luciano, F., et al., Oncogene 22(43):6785-6793 (2003). Sunters, A., et al., J. Biol. Chem. 278(50):49795-49805 (2003). Reginato, M.J., et al., Nat. Cell Biol. 5(8):733-740 (2003). Chen, D., et al., EMBO J. 21(24):6801-6810 (2002). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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