LOXL1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLOXL1
Clonepolyclonal
Host Speciesn/a
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionDescription: Rabbit IgG polyclonal antibody for Lysyl oxidase homolog 1(LOXL1) detection. Tested with WB, IHC-P in Human. Background: Lysyl oxidase homolog 1, also known as LOXL1, is an enzyme which in humans is encoded by the LOXL1 gene. This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human LOXL1 (397-425aa AEEKCLASTAYAPEATDYDVRVLLRFPQR), different from the related mouse sequence by one amino acid. Ig Type: Rabbit IgG
Other Names[Lysyl oxidase homolog 1; Lysyl oxidase like 1; LOL; LOXL; Lysyl oxidase homolog 1; Lysyl oxidase like protein 1; lysyl oxidase-like 1], [LOXL1; LOXL1; LOL; LOXL; LOXL; LOL]
Gene, Accession #[LOXL1], Gene ID: 4016, NCBI: NP_005567.2, UniProt: Q08397
Catalog #MBS178242
Price$315
Order / More InfoLOXL1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Kenyon K, Modi WS, Contente S, Friedman RM (September 1993). A novel human cDNA with a predicted protein similar to lysyl oxidase maps to chromosome 15q24-q25. The Journal of Biological Chemistry 268 (25): 18435-7. 2. Liu X, Zhao Y, Gao J, Pawlyk B, Starcher B, Spencer JA, Yanagisawa H, Zuo J, Li T (Feb 2004). Elastic fiber homeostasis requires lysyl oxidase-like 1 protein. Nat. Genet. (United States) 36 (2): 178-82. 3. Entrez Gene: LOXL1 lysyl oxidase-like 1.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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