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Antigenic Specificity | NOX4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NOX4 antibody is human, mouse, and rat reactive. At least four isoforms of NOX4 are known to exist. NOX4 is predicted to not cross-react with other NOX proteins. The NOX family of NAPDH oxidases is comprised of seven transmembrane proteins that oxidize intracellular NAPDH/NADH, causing electron transport across the membrane and the reduction of molecular oxygen to superoxide (1). NOX4 is is expressed in multiple tissues and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS) (2,3). Unlike other NOX proteins, NOX4 does not require cytosolic subunits and thus is constitutively active (4). The function of NOX4 remains unclear as it plays both protective and deleterious roles in cellular metabolism. |
Immunogen | Immunogen: NOX4 antibody was raised against a 14 amino acid peptide near the amino terminus of human NOX4. Buffer: NOX4 antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [NAPDH oxidase 4; NOX-4; RENOX; KOX; KOX-1; NADPH oxidase 4], [NOX4; NOX4; KOX; KOX-1; RENOX; RENOX; KOX-1] |
Gene, Accession # | [NOX4], Gene ID: 50507, NCBI: NP_058627 |
Catalog # | MBS153477 |
Price | $375 |
Order / More Info | NOX4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |