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Antigenic Specificity | UBE3B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: UBE3B Polyclonal Antibody detects endogenous levels of UBE3B protein. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: e1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin-protein ligases. UBE3B (ubiquitin protein ligase E3B) encodes a member of the E3 ubiquitin-conjugating enzyme family which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme and transfers the ubiquitin to the targeted substrates. A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human UBE3B at AA range: 550-630 |
Other Names | [Rabbit UBE3B; UBE3B; Ubiquitin-protein ligase E3B] |
Gene, Accession # | [UBE3B], Gene ID: 89910, NCBI: NP_001257378.1, UniProt: Q7Z3V4 |
Catalog # | MBS9707548 |
Price | $130, $220, $325 |
Order / More Info | UBE3B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |