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Antigenic Specificity | HTATIP2 |
Clone | [AT5D6] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, k |
Format | Protein A purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1 mg/ml |
Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HTATIP2, also known as TIP30, is a member of the short-chain dehydrogenases/reductases (SDR) family. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in This protein are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for HTATIP2 in antitumor therapy. |
Immunogen | Immunogen: Recombinant human HTATIP2 (1-242aa) purified from E. coli |
Other Names | [Oxidoreductase HTATP2; CC3; TIP30; SDR44u1; Oxidoreductase HTATP2; HTATIP 2; HTATIP-2; CC-3; TIP 30; TIP-30], [HTATIP2; HTATIP2; CC3; TIP30; SDR44U1] |
Gene, Accession # | [HTATIP2], Gene ID: 10553, NCBI: AAH15358 |
Catalog # | MBS200450 |
Price | $240, $315 |
Order / More Info | HTATIP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | Shtivelman E., et al. (1997) Oncogene. 14 (18): 2167-73. ; Xiao H., et al. (1998) Proc Natl Acad Sci u S A. 95 (5): 2146-2151. |