CD74 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD74 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CD74 antibody detects endogenous levels of total CD74. Description: The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.Function: Plays a critical role in MHC class II antigen processin |
| Immunogen | Immunogen: A synthesized peptide derived from human CD74 Subcellular Location: Cell Membrane. Endoplasmic Reticulum Membrane. Golgi Apparatus > Trans-Golgi Network. Endosome. Lysosome. Transits through a number of intracellular compartments in the endocytic pathway. It can either undergo proteolysis or reach the cell membrane. Predicted Cross Reactivity: Sheep, Rabbit, Dog, Chicken Similarity: Sheep (80%), Rabbit (80%), Dog (90%), Chicken (80%) |
| Other Names | [CD 74; CD74; CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated); CD74 antigen; CD74 molecule; CD74 molecule, major histocompatibility complex, class II invariant chain; CLIP; DHLAG; Gamma chain of class II antigens; HG2A_HUMAN; HLA class II histocompatibility antigen gamma chain; HLA DR antigens associated invariant chain; HLA DR gamma; HLA-DR antigens-associated invariant chain; HLA-DR-gamma; HLADG; HLADR antigens associated invariant chain; Ia antigen associated invariant chain; Ia antigen-associated invariant chain; Ia associated invariant chain; Ia gamma; Ii; Invariant polypeptide of major histocompatibility complex class II antigen associated; la-gamma; Major histocompatibility complex class II invariant chain; MHC HLA DR gamma chain; MHC HLA-DR gamma chain; p33; p35; Protein 41] |
| Gene, Accession # | [CD74], Gene ID: 972, NCBI: NP_001020329.1, UniProt: P04233 |
| Catalog # | MBS9608085 |
| Price | $240, $280 |
| Order / More Info | CD74 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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