FADD Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFADD
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.1 mg
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionSpecificity: Western blot analysis of extracts of various cell lines, using FADD antibody. The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T ce
ImmunogenImmunogen: Recombinant protein of human FADD
Other Names[FADD; FAS-associated death domain protein; FAS-associated death domain protein; Fas associated via death domain; FAS-associating death domain-containing protein; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity; Protein FADD]
Gene, Accession #[FADD], Gene ID: 8772, NCBI: CAG33019.1
Catalog #MBS4150632
Price$385
Order / More InfoFADD Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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