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Antigenic Specificity | CEACAM3 (C-term), 163-191 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CEACAM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-191 amino acids from the C-terminal region of human CEACAM3. This gene encodes a member of the family ofcarcinoembryonic antigen-related cell adhesion molecules (CEACAMs),which are used by several bacterial pathogens to bind and invadehost cells. The encoded transmembrane protein directs phagocytosisof several bacterial species that is dependent on the small GTPaseRac. It is thought to serve an important role in controllinghuman-specific pathogens by the innate immune system. Alternativelyspliced transcript variants have been described, but theirbiological validity has not been determined. |
Immunogen | n/a |
Other Names | [Carcinoembryonic antigen-related cell adhesion molecule 3; Carcinoembryonic antigen CGM1; CD66d; CEACAM3; CD66D; CGM1] |
Gene, Accession # | [CEACAM3], Gene ID: 1084, NCBI: NP_001264092.1, UniProt: P40198 |
Catalog # | MBS9211143 |
Price | $165, $370 |
Order / More Info | CEACAM3 (C-term), 163-191 Antibody from MYBIOSOURCE INC. |
Product Specific References | Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Tsavaris, N., et al. J Chemother 21(6):673-680(2009) Skubitz, K.M., et al. J Transl Med 6, 78 (2008) : Stern-Ginossar, N., et al. J. Immunol. 179(7):4424-4434(2007) Ali, C.W., et al. J Gastrointest Cancer 38 (2-4), 108-114 (2007) : |