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Antigenic Specificity | TRAF2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for TNF receptor-associated factor 2(TRAF2) detection. Tested with WB, IHC-P in Human, Mouse, Rat. Background: TRAF2(TNF Receptor-Associated Factor 2), also called TRAP, is a protein that in humans is encoded by the TRAF2 gene. The protein encoded by this gene is a member of the TNF receptor(TNFR) associated factor(TRAF) protein family. TRAF2 is a common signal transducer for TNFR2 and CD40 that mediates activation of NF-kappa-B. Rothe et al.(1996) identified ITRAF, which binds to TRAF1, TRAF2, and TRAF3, and that when overexpressed inhibits TRAF2-mediated NF-kappa-B activation. They proposed that ITRAF is an inhibitor of TRAF function that regulates TRAF protein activity by sequestering TRAFs in |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human TRAF2 (305-325aa RQHRLDQDKIEALSSKVQQLE), different from the related rat and mouse sequences by one amino acid. |
Other Names | [TNF receptor-associated factor 2; TNF receptor-associated factor 2; E3 ubiquitin-protein ligase TRAF2; MGC: 45012; OTTHUMP00000022625; OTTHUMP00000064745; TNF receptor associated factor 2; TNF receptor-associated factor 2; TNF receptor-associated protein; TRAF 2; TRAF2; TRAF2_HUMAN; TRAP 3; TRAP; TRAP3; Tumor necrosis factor type 2 receptor associated protein 3; Tumor necrosis factor type 2 receptor-associated protein 3], [TRAF2; TRAF2; TRAP; TRAP3; MGC:45012; TRAP3] |
Gene, Accession # | [TRAF2], Gene ID: 7186, NCBI: Q12933.2, UniProt: Q12933 |
Catalog # | MBS176268 |
Price | $315 |
Order / More Info | TRAF2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |