GAD1 (C-term), 514-543 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | GAD1 (C-term), 514-543 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.27 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This GAD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 514-543 amino acids from the C-terminal region of human GAD1. This gene encodes one of several forms of glutamic aciddecarboxylase, identified as a major autoantigen ininsulin-dependent diabetes. The enzyme encoded is responsible forcatalyzing the production of gamma-aminobutyric acid fromL-glutamic acid. A pathogenic role for this enzyme has beenidentified in the human pancreas since it has been identified as anautoantigen and an autoreactive T cell target in insulin-dependentdiabetes. This gene may also play a role in the stiff man syndrome.Deficiency in this enzyme has been shown to lead to pyridoxine |
| Immunogen | n/a |
| Other Names | [Glutamate decarboxylase 1; 67 kDa glutamic acid decarboxylase; GAD-67; Glutamate decarboxylase 67 kDa isoform; GAD1; GAD; GAD67] |
| Gene, Accession # | [GAD1], Gene ID: 2571, NCBI: NP_000808.2, UniProt: Q99259 |
| Catalog # | MBS9215120 |
| Price | $165, $370 |
| Order / More Info | GAD1 (C-term), 514-543 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Lanoue, A.C., et al. Exp. Neurol. 226(1):207-217(2010) Jia, P., et al. Schizophr. Res. 122 (1-3), 38-42 (2010) : Terranova, C., et al. Alcohol 44(5):407-413(2010) Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010) Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) : |
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MYBIOSOURCE INC.
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