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Antigenic Specificity | Histone H2AZ; |
Clone | [RM215] |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | Protein A purified |
Size | 0.025 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB); Immunocytochemistry (ICC); ELISA (EIA); Multiplex |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit monoclonal antibody to detect Histone H2AZ. Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin; limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation; DNA repair; DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones; also called histone code; and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division. |
Immunogen | Immunogen: A peptide corresponding to the C-terminus of human Histone H2AZ |
Other Names | [Histone H2A.Z; H2A/z; H2AFZ], [H2AFZ] |
Gene, Accession # | [H2AZ], Gene ID: 3015, NCBI: NP_002097.1, UniProt: P0C0S5 |
Catalog # | MBS846020 |
Price | $245 |
Order / More Info | Histone H2AZ; Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |