Edit |   |
---|---|
Antigenic Specificity | Phospho-Akt2 (Ser474) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB); ELISA (EIA); Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal antibody to detect endogenous levels of Akt2 protein phosphorylated at S474 in human; mouse and rat. AKT2 is a putative oncogenic protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. Furthermore; AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression of AKT2 contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins. |
Immunogen | Immunogen: Synthesized peptide derived from human Akt2 around the phosphorylation site of S474 |
Other Names | [AKT2; RAC-beta serine/threonine-protein kinase; Protein kinase Akt-2; Protein kinase B beta; PKB beta; RAC-PK-beta], [AKT2; PKB beta] |
Gene, Accession # | [Akt2], Gene ID: 208, NCBI: NP_001317440.1, UniProt: P31751 |
Catalog # | MBS846124 |
Price | $335 |
Order / More Info | Phospho-Akt2 (Ser474) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |