Human LAG-3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human LAG-3 |
| Clone | [3C39] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | LAG-3 (Lymphocyte activation gene-3), also known as CD223, is a member of the immunoglobulin superfamily (IgSF). The mature LAG-3 protein is a 496 amino acid (aa) membrane protein with a 421 aa extracellular region that contains four IgSF domains, a 21 aa transmembrane region and a 54 aa cytoplasmic region. LAG-3 and CD4 molecules share < 20% aa sequence homology but have a similar structure. Both molecules bind to MHC class II. LAG-3 binds to MHC class II with higher affinity than CD4. Both LAG-3 and CD4 genes are located on the distal part of the short arm of chromosome 12. |
| Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of LAG-3 (also called CD223). |
| Other Names | [LAG3; CD223], [LAG3; LAG3; CD223; FDC; LAG-3] |
| Gene, Accession # | [LAG-3], Gene ID: 3902, NCBI: NP_002277.4, UniProt: P18627 |
| Catalog # | MBS690230 |
| Price | $490 |
| Order / More Info | Human LAG-3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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