IL27RA Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIL27RA
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: IL27RA antibody detects endogenous levels of total IL27RA. Function: Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms.Similarity: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.The box 1 motif is required for JAK interaction and/or activation. Belongs to the type I cytokine receptor family. Type 2 subfamily.
ImmunogenImmunogen: A synthesized peptide derived from human IL27RA Subcellular Location: Membrane. Tissue Specificity: Highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. Weakly expressed in other tissues examined including heart, brain, fetal and adult lung, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine, kidney and colon. In the lymphoid system, higher level expression in CD4 T-cell subsets than in CD8 T-cell subsets. Al
Other Names[Class I cytokine receptor; CRL1; Cytokine receptor-like 1; I27RA_HUMAN; IL-27 receptor subunit alpha; IL-27R subunit alpha; IL-27R-alpha; IL-27RA; IL27R alpha; IL27R; Il27ra; Interleukin 27 receptor alpha chain precursor; Interleukin 27 receptor; Interleukin-27 receptor subunit alpha; Protein CRL1; T cell cytokine receptor type 1; TCCR; Type 1 T cell cytokine receptor; Type I T-cell cytokine receptor; WSX-1; WSX1; ZcytoR1]
Gene, Accession #[IL27RA], Gene ID: 9466, NCBI: NP_004834.1, UniProt: Q6UWB1
Catalog #MBS9603018
Price$240, $280
Order / More InfoIL27RA Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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