Human Interferon Regulatory Factor-3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Interferon Regulatory Factor-3 |
| Clone | [P3F10AT] |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 k |
| Format | Protein G purified |
| Size | 0.005 mg, 0.02 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Introduction: Members of the Interferon regulatory factor (IRF) family regulate gene expression critical to immune response, hemopoiesis, and proliferation. IRF-3 is a member of the IRF family, and is distinct from other family members. Its transcriptional activity is regulated solely by posttranslational modifications. It plays a crucial role in activation of innate immunity and inflammation in response to viral infection. IRF-3 mediates interferon-stimulated response element (isre) promoter activation. Functions as a molecular switch for antiviral activity. Dsrna generated during the course of an viral infection leads to IRF3 phosphorylation on the c-terminal serine/threonine cluster. This induces a conformational change, leading to its d |
| Immunogen | Immunogen: Anti-human IRF3 mAb, is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with Recombinant human IRF3 amino acids 108-166 purified from E Coli. |
| Other Names | [IRF3; Interferon Regulatory Factor-3, Mouse Human; IRF-3; IRF3; Interferon Regulatory Factor 3], [IRF3; IRF3; IRF-3] |
| Gene, Accession # | [IRF3], Gene ID: 3661, NCBI: NP_001184056.1 |
| Catalog # | MBS140272 |
| Price | $140, $205, $505 |
| Order / More Info | Human Interferon Regulatory Factor-3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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