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Antigenic Specificity | PACS2 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against PACS2. It was validated on Western Blot using a cell lysate as a positive control.Target Description: PACS2 is the multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer,PACS2 translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death.PACS2 may also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PACS2 |
Other Names | [phosphofurin acidic cluster sorting protein 2 isoform 2; Phosphofurin acidic cluster sorting protein 2; phosphofurin acidic cluster sorting protein 2; phosphofurin acidic cluster sorting protein 2; PACS1-like protein] |
Gene, Accession # | [PACS2], Gene ID: 23241, NCBI: NP_056012, UniProt: Q86VP3 |
Catalog # | MBS3210362 |
Price | $335 |
Order / More Info | PACS2 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |