ADAMTS4 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ADAMTS4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: ADAMTS4 antibody detects endogenous levels of total ADAMTS4. Description: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan |
| Immunogen | Immunogen: A synthesized peptide derived from human ADAMTS4 Subcellular Location: Secreted > Extracellular Space > Extracellular Matrix. Tissue Specificity: Expressed in brain, lung and heart (PubMed:23897278). Expressed at very low level in placenta and skeletal muscles (PubMed:23897278). Isoform 2: Detected in osteoarthritic synovium (PubMed:16723216, PubMed:23897278). Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (91%), Bo |
| Other Names | [A disintegrin and metalloproteinase with thrombospondin motifs 4; A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 4; A disintegrin like and metalloprotease with thrombospondin type 1 motif 4; ADAM metallopeptidase with thrombospondin type 1 motif 4; ADAM TS 4; ADAM TS4; ADAM-TS 4; ADAM-TS4; ADAMTS 2; ADAMTS 4; ADAMTS-4; ADAMTS2; ADAMTS4; ADAMTS4 protein; ADMP 1; ADMP-1; ADMP1; Aggrecanase 1; Aggrecanase-1; Aggrecanase1; ATS4_HUMAN; KIAA0688] |
| Gene, Accession # | [ADAMTS4], Gene ID: 9507, NCBI: NP_001307265.1, UniProt: O75173 |
| Catalog # | MBS9607639 |
| Price | $240, $280 |
| Order / More Info | ADAMTS4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Zhou S, Lu W, Chen L, Ge Q, Chen D, Xu Z, Shi D, Dai J, Li J, Ju H, Cao Y, Qin J, Chen S, Teng H, Jiang Q; Journal: Sci Rep. AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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