Integrin alphaV, beta5 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Integrin alphaV, beta5 |
| Clone | [2Q873] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | purified |
| Size | 0.1 mg |
| Concentration | 1mg/ml |
| Applications | ELISA (EL/EIA), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes human integrin alphaVbeta5. Does not recognize integrin alphaVbeta3 or alpha5beta1. Binds to the alphaVbeta5 complex. Has a Kd of 2.8 nM in Mn2+, 4.0 nM in Ca2+and 2.9 nM in buffer lacking cation. Thus, cations do not significantly affect the binding to alphaVbeta5. Does not block ligand binding to purified alphaVbeta5, nor does it block cell adhesion mediated through this receptor. Integrins are transmembrane proteins that mediate interactions between adhesion molecules on adjacent cells and/or the extracellular matrix (ECM). Integrins have diverse roles in several biological processes including cell migration during development and wound healing, cell differentiation, and apoptosis. Their activities can also regulate the metast |
| Immunogen | Immunogen: Generated against human integrin alphaVbeta5 purified from placental tissue and depleted of integrin alphaVbeta3. |
| Other Names | [-Integrin alphaV, beta5], [ITGB5; ITGB5] |
| Gene, Accession # | Gene ID: 3693, NCBI: NP_002204.2, UniProt: P18084 |
| Catalog # | MBS601117 |
| Price | $680 |
| Order / More Info | Integrin alphaV, beta5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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