Edit |   |
---|---|
Antigenic Specificity | SYNPO |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SYNPO Antibody: SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity. |
Immunogen | Immunogen: SYNPO antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SYNPO. Buffer: SYNPO Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [SYNPO; KIAA1029; Synaptopodin; synaptopodin], [SYNPO; SYNPO; KIAA1029] |
Gene, Accession # | [SYNPO], Gene ID: 11346, NCBI: NP_001159680, UniProt: Q8N3V7 |
Catalog # | MBS151009 |
Price | $375 |
Order / More Info | SYNPO Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |