IL13 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIL13
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: IL13 antibody detects endogenous levels of total IL13. Description: IL-13 is produced by T cells and is important in the TH2 response. IL-13 targets include B cells, eosinophils, fibroblasts, mast cells and macrophages (1-3). IL-13 binds specifically to IL-13Ralpha1 that complexes with IL-4Ralpha to form the Type II IL-4R. Jak1 and Tyk2 are activated and signal through Stat3 and Stat6 (6). IL-13Ralpha2 is a different gene product, lacks the intracellular domain, does not complex with IL-4Ralpha and does not signal (1, 6, 7). The extracellular domain of IL-13Ralpha2 is often elevated in diseased states. IL-13 plays key roles in airway hyperresponsiveness (AHR) of allergic asthma (1, 4, 5) and modulates resistance to parasitic or
ImmunogenImmunogen: A synthesized peptide derived from human IL13 Subcellular Location: Secreted.
Other Names[Allergic rhinitis; ALRH; BHR1; Bronchial hyperresponsiveness 1 (bronchial asthma); IL 13; IL-13; Il13; IL13_HUMAN; Interleukin 13; Interleukin-13; MGC116786; MGC116788; MGC116789; NC30; P600]
Gene, Accession #[IL13], Gene ID: 3596, NCBI: NP_002179.2, UniProt: P35225
Catalog #MBS9607468
Price$240, $280
Order / More InfoIL13 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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