DC-SIGN Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-DC-SIGN antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | DC-SIGN |
| Clone | [8B6] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN. ICAM-3 is the natural ligand for DC-SIGN. A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR are known to exisit (8). The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum. |
| Immunogen | Immunogen Type: Recombinant protein Immunogen Description: A recombinant His-tagged protein fragment corresponding to the extracellular region of human DC-SIGN. |
| Other Names | [DC-SIGN (8B6), Dendritic cell-specific ICAM-3-grabbing nonintegrin 1] |
| Gene, Accession # | [DC-SIGN], Gene ID: 30835, NCBI: NP_001138365.1, UniProt: Q9NNX6 |
| Catalog # | MBS9400266 |
| Price | $320 |
| Order / More Info | DC-SIGN Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies