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Antigenic Specificity | Phospho-STAT2 (Tyr690) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-STAT2 (Tyr690) antibody detects endogenous levels of STAT2 only when phosphorylated at Tyrosine 690. Description: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo-or heterodimers that translocate to the cell nucleus where they act as transcription activators.Function: Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs |
Immunogen | Immunogen: A synthesized peptide derived from human STAT2 around the phosphorylation site of Tyrosine 690 Subcellular Location: Cytoplasm. Nucleus. Translocated into the nucleus upon activation by IFN-alpha/beta. Predicted Cross Reactivity: Pig, Horse, Dog Similarity: Pig (82%), Horse (82%), Dog (91%) |
Other Names | [Homo sapiens interferon alpha induced transcriptional activator; interferon alpha induced transcriptional activator; ISGF 3; ISGF3; MGC59816; P113; signal transducer and activator of transcription 2 113kD; Signal transducer and activator of transcription 2; STAT113; Stat2; STAT2_HUMAN] |
Gene, Accession # | [STAT2], Gene ID: 6773, NCBI: NP_005410.1, UniProt: P52630 |
Catalog # | MBS9601111 |
Price | $240, $280 |
Order / More Info | Phospho-STAT2 (Tyr690) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |