Phospho-STAT2 (Tyr690) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-STAT2 (Tyr690)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: Phospho-STAT2 (Tyr690) antibody detects endogenous levels of STAT2 only when phosphorylated at Tyrosine 690. Description: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo-or heterodimers that translocate to the cell nucleus where they act as transcription activators.Function: Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs
ImmunogenImmunogen: A synthesized peptide derived from human STAT2 around the phosphorylation site of Tyrosine 690 Subcellular Location: Cytoplasm. Nucleus. Translocated into the nucleus upon activation by IFN-alpha/beta. Predicted Cross Reactivity: Pig, Horse, Dog Similarity: Pig (82%), Horse (82%), Dog (91%)
Other Names[Homo sapiens interferon alpha induced transcriptional activator; interferon alpha induced transcriptional activator; ISGF 3; ISGF3; MGC59816; P113; signal transducer and activator of transcription 2 113kD; Signal transducer and activator of transcription 2; STAT113; Stat2; STAT2_HUMAN]
Gene, Accession #[STAT2], Gene ID: 6773, NCBI: NP_005410.1, UniProt: P52630
Catalog #MBS9601111
Price$240, $280
Order / More InfoPhospho-STAT2 (Tyr690) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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