Synaptophysin Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Synaptophysin |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Synaptophysin, also known as the major synaptic vesicle protein p38, is an integral membrane protein that regulates synaptic vesicle endocytosis. It is the most abundant synaptic vesicle protein by mass, accounting for about 10% of total vesicle protein.1 The protein is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38kDa. It is present in neuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for neuroendocrine tumors, and its ubiquity at the synapse has led to the use of synaptophysin immunostaining for quantification of synapses.2 |
| Immunogen | Immunogen: A synthetic peptide (conjugated with KLH) corresponding to TOPO_MOD residues of mouse Synaptophysin. |
| Other Names | [Synaptophysin], [SYP; SYP; MRXSYP] |
| Gene, Accession # | Gene ID: 6855, NCBI: NP_003170.1, UniProt: P08247 |
| Catalog # | MBS355146 |
| Price | $275 |
| Order / More Info | Synaptophysin Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Kwon, S. E., Chapman, E. R. Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in central neurons. Neuron 70: 847-854, 2011. 2. Calhoun ME, Jucker M, Martin LJ, Thinakaran G, Price DL, Mouton PR (December 1996). Comparative evaluation of synaptophysin-based methods for quantification of synapses. J. Neurocytol. 25 (12): 821-8. |
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