Edit |   |
---|---|
Antigenic Specificity | CDC42/RHO/RAC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total CDC42/RHO/RAC protein. The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multip |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human Cell division cycle 42 |
Other Names | [G25K; CDC42Hs] |
Gene, Accession # | [CDC42/RHO/RAC], Gene ID: 998, NCBI: NP_001034891.1, UniProt: P60953 |
Catalog # | MBS9409528 |
Price | $255 |
Order / More Info | CDC42/RHO/RAC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |