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Antigenic Specificity | IL-10 |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Interleukine 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. |
Immunogen | Immunogen: Purified recombinant fragment of human IL-10 expressed in E. Coli. |
Other Names | [3C12C12], [IL10; IL10; CSIF; TGIF; GVHDS; IL-10; IL10A; IL-10; CSIF] |
Gene, Accession # | [IL-10], Gene ID: 3586, NCBI: NP_000563.1, UniProt: P22301 |
Catalog # | MBS850057 |
Price | $280 |
Order / More Info | IL-10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |