RET Proto-oncogene Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRET Proto-oncogene
Clone[RET/2599]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b, kappa
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionThe Ret proto-oncogene is structurally related to the growing family of tyrosine kinase transmembrane receptors and is involved in GDNF signaling. RET expression is reported in several regions of the central nervous system; in the developing cranial nerve ganglia and a subset of cells within dorsal root ganglia, in motor neurons in the spinal cord and hindbrain, in neuro-retina and the growing tips of the renal collecting ducts in developing kidney.Alterations in RETgene are associated with diseases including papillary thyroid carcinoma, multiple endocrine neoplasia (type 2A and 2B), familial medullary thyroid carcinoma, and a congenital developmental disorder known as Hirschsprung's disease.
ImmunogenImmunogen: Recombinant fragment (around aa 702-848) of human RET protein (exact sequence is proprietary)
Other Names[Cadherin family member 12 (CDHF12); Cadherin related family member 16 (CDHR16); ELKS; HSCR1; Hydroxyaryl protein kinase; MEN2A; MEN2B; MTC1; Multiple endocrine neoplasia and medullary thyroid carcinoma 1; Oncogene RET; Proto-oncogene c-Ret; Proto-oncogene tyrosine-protein kinase receptor ret; PTC; RET; RET ELE1; RET51; RET9]
Gene, Accession #[RET], Gene ID: 5979, NCBI: NP_065681.1, UniProt: P07949
Catalog #MBS4381222
Price$190, $340, $340
Order / More InfoRET Proto-oncogene Antibody from MYBIOSOURCE INC.
Product Specific ReferencesAiraksinen, M.S. et al. (1999) Mol Cell Neurosci 13, 313-25.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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