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Antigenic Specificity | Hax1b |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least four isoforms of Hax1 are known to exist. This antibody is predicted to recognize Hax1b. The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 10 amino acid peptide near the amino terminus of human Hax1b. |
Other Names | [Hax1b, HS-1 associated protein X-1, HCLS1 associated protein X-1, HCLSBP1, HS1BP1] |
Gene, Accession # | [Hax1b], Gene ID: 10456, NCBI: NP_001018238 |
Catalog # | MBS9402588 |
Price | $320 |
Order / More Info | Hax1b Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |