Hax1b Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHax1b
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionSpecificity: At least four isoforms of Hax1 are known to exist. This antibody is predicted to recognize Hax1b. The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows
ImmunogenImmunogen Type: Peptide Immunogen Description: Raised against a 10 amino acid peptide near the amino terminus of human Hax1b.
Other Names[Hax1b, HS-1 associated protein X-1, HCLS1 associated protein X-1, HCLSBP1, HS1BP1]
Gene, Accession #[Hax1b], Gene ID: 10456, NCBI: NP_001018238
Catalog #MBS9402588
Price$320
Order / More InfoHax1b Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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