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Antigenic Specificity | Synaptotagmin 1 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Synaptotagmin-1 is a protein that in humans is encoded by the SYT1 gene. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse.Protein Function: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also bee |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence of human Synaptotagmin 1 (RRPIAQWHTLQVEEEVDAMLAVKK). Subcellular Localization: Cytoplasmic vesicle, secretory vesicle membrane. Tissue Specificity: Expressed in melanocytes (PubMed: 23999003). |
Other Names | [Synaptotagmin-1; Synaptotagmin I; SytI; p65; SYT1; SVP65; SYT] |
Gene, Accession # | [SYT1], Gene ID: 6857, NCBI: NP_001129277.1, UniProt: P21579 |
Catalog # | MBS1750760 |
Price | $315 |
Order / More Info | Synaptotagmin 1 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |