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Antigenic Specificity | FasL |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.03 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~31 kDa FasL in samples of mouse and rat origins. A ~70 kDa band, possible represents thr FasL and Fas complex can also be detected. Background: Fas/Apo-1/CD95 is a cell surface type-I membrane glycoprotein with an apparent molecular weight of 44 kDa on SDS-PAGE. Fas is a member of the TNFR family that includes TNFR1, TNFR2, CD27, CD30, and CD40. Binding of Fas-ligand (FasL) to Fas or crosslinking of Fas by anti-Fas monoclonal antibodies leads to apoptosis in Fas expressing cells. Both Fas and TNF-R contain the 70 amino acids cytoplasmic death domain that is responsible for transmitting signal for apoptosis. |
Immunogen | Immunogen: Synthetic peptide mapping to the C-terminus of rat FasL |
Other Names | [FASLG; FASL; FasL; CD95L; APT1LG1; CD178; APTL; TNFSF6], [Fasl; Faslg; gld; CD178; CD95L; Fas-L; Faslg; CD95-L; Tnfsf6; APT1LG1; Apt1lg1; Cd95l; Fasl; gld; Tnfsf6; CD95-L; Fas ligand; FasL; sFasL; APL; FasL ICD; SPA] |
Gene, Accession # | [FasL], Gene ID: 14103, NCBI: NP_034307.1, UniProt: P41047 |
Catalog # | MBS840226 |
Price | $150, $290 |
Order / More Info | FasL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |