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Antigenic Specificity | Human Nuclear receptor subfamily 2 group C member 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Plays a fundamental role in early embryonic development and embryonic stem cells. Required for normal spermatogenesis an |
Immunogen | Immunogen: Recombinant human Nuclear receptor subfamily 2 group C member 2 protein (240-380aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-8619 / sc-8620 |
Other Names | [Orphan nuclear receptor TAK1; Orphan nuclear receptor TR4; Testicular receptor 4; NR2C2; TAK1; TR4], [NR2C2; NR2C2; TR4; TAK1; TAK1; TR4] |
Gene, Accession # | [NR2C2], Gene ID: 7182, NCBI: NP_001278623.1, UniProt: P49116 |
Catalog # | MBS1493595 |
Price | $120, $160 |
Order / More Info | Human Nuclear receptor subfamily 2 group C member 2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |