PD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target)
Clone[PDL1/2741]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsELISA (EIA)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionSpecificity: PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.
ImmunogenImmunogen: Recombinant fragment of human CD274 protein (around aa39-191) (exact sequence is proprietary)
Other Names[B7 homolog 1; B7-H1; CD274; PD-L1; PDCD1 ligand 1; PDCD1L1; PDCD1LG1; Programmed cell death 1 ligand 1]
Gene, Accession #[CD274], Gene ID: 29126, NCBI: NP_001254635.1, UniProt: Q9NZQ7
Catalog #MBS4380955
Price$190, $340, $340
Order / More InfoPD-L1/PDCD1LG1/CD274/B7-H1 (Cancer Immunotherapy Target) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesDong, H., et al. 1999. B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat. Med. 5: 1365-1369
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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