Edit |   |
---|---|
Antigenic Specificity | PARP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total PARP2 protein. Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.Sugano S., Nat. Genet. 36:40-45(2004).de Murcia G.M., J. Biol. Chem. 277:23028-23036(2002).Bennett K.L., Submitted (OCT-2008). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human PARP2. |
Other Names | [Poly [ADP-ribose] polymerase 2; PARP-2; NAD(+) ADP-ribosyltransferase 2; Poly[ADP-ribose] synthetase 2; pADPRT-2] |
Gene, Accession # | [PARP2], Gene ID: 10038, NCBI: NP_001036083.1, UniProt: Q9UGN5 |
Catalog # | MBS9412647 |
Price | $200, $255 |
Order / More Info | PARP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |