RET Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRET
Clone[188CT11.2.3]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgM,K
Formatascites
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThis RET Monoclonal antibody was raised using purified His-tagged recombinant human RET. This gene, a member of the cadherin superfamily, encodesone of the receptor tyrosine kinases, which are cell-surfacemolecules that transduce signals for cell growth anddifferentiation. This gene plays a crucial role in neural crestdevelopment, and it can undergo oncogenic activation in vivo and invitro by cytogenetic rearrangement. Mutations in this gene areassociated with the disorders multiple endocrine neoplasia, typeIIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease,and medullary thyroid carcinoma. Two transcript variants encodingdifferent isoforms have been found for this gene. Additionaltransc
Immunogenn/a
Other Names[Proto-oncogene tyrosine-protein kinase receptor Ret; Cadherin family member 12; Proto-oncogene c-Ret; Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment; RET; CDHF12; CDHR16; PTC; RET51]
Gene, Accession #[RET], Gene ID: 5979, NCBI: NP_065681.1, UniProt: P07949
Catalog #MBS9200010
Price$370
Order / More InfoRET Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSiqueira, D.R., et al. Endocr. Relat. Cancer 17(4):953-963(2010) Gockel, H.R., et al. Hum. Genet. 128(4):353-364(2010) Kim, H.K., et al. Anticancer Res. 30(9):3621-3627(2010) Pacini, F., et al. Clin Oncol (R Coll Radiol) 22(6):475-485(2010) Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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