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Antigenic Specificity | APOBEC3F |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected targe |
Immunogen | Immunogen: Recombinant Human DNA dC->dU-editing enzyme APOBEC-3F protein (139-287AA) |
Other Names | [DNA dC->dU-editing enzyme APOBEC-3F; Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F; A3F; APOBEC3F] |
Gene, Accession # | [APOBEC3F], Gene ID: 200316, NCBI: NP_001006667.1, UniProt: Q8IUX4 |
Catalog # | MBS7105322 |
Price | $160, $235 |
Order / More Info | APOBEC3F Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |