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Antigenic Specificity | BAD |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total BAD protein. Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 By similarity. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.Wang H.-G., Cell 87:629-638(1996).Ottilie S., J. Biol. Chem. 272:30866-30872(1997).The MGC Project Team, Genome Res. 14:2121-2127(2004). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from Internal of human BAD. |
Other Names | [BAD; BBC6; BCL2L8; Bcl-XL/Bcl-2 associated death promoter; Bcl-2 binding component 6] |
Gene, Accession # | [BAD], Gene ID: 572, NCBI: NP_004313.1, UniProt: Q92934 |
Catalog # | MBS9402389 |
Price | $200, $255 |
Order / More Info | BAD Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |