BAD Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBAD
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total BAD protein. Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 By similarity. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.Wang H.-G., Cell 87:629-638(1996).Ottilie S., J. Biol. Chem. 272:30866-30872(1997).The MGC Project Team, Genome Res. 14:2121-2127(2004).
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from Internal of human BAD.
Other Names[BAD; BBC6; BCL2L8; Bcl-XL/Bcl-2 associated death promoter; Bcl-2 binding component 6]
Gene, Accession #[BAD], Gene ID: 572, NCBI: NP_004313.1, UniProt: Q92934
Catalog #MBS9402389
Price$200, $255
Order / More InfoBAD Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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