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Antigenic Specificity | Mouse CD27 |
Clone | [LG.3A10] |
Host Species | Hamster |
Reactive Species | n/a |
Isotype | IgG |
Format | fluorescein (FITC) conjugate |
Size | 0.1 mg |
Concentration | IgG concentration 0.5mg/ml |
Applications | Flow cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Clone LG.3A10 recognises mouse, rat and human CD27, a member of the tumour necrosis factor receptor superfamily. It is expressed in the thymus and spleen, but not in non-lymphoid tissues. CD27 acts as a ligand for CD70, which is expressed in T and B cells, and acts as a costimulatory signal in lymphocyte proliferation and immunoglobulin production. CD27 lacks a death domain in its short cytoplasmic tail, but can induce apoptosis by binding with the apoptosis regulatory protein Siva (also known as CD27-binding protein). Clone LG.3A10 recognises mouse, rat and human CD27, a member of the tumour necrosis factor receptor superfamily. It is expressed in the thymus and spleen, but not in non-lymphoid tissues. CD27 acts as a ligand fo |
Immunogen | Immunogen: Armenian hamster fibroblast line ARHO12 transfected with mouse CD27 cDNA. Buffer Solution: Phosphate buffered saline Target Species: Mouse |
Other Names | [CD27 antigen; CD27 antigen; CD antigen 27; tumor necrosis factor receptor superfamily, member 7; CD27 molecule], [Cd27; Tnfrsf7] |
Gene, Accession # | [CD27], Gene ID: 500318, NCBI: NP_001019506.1 |
Catalog # | MBS224469 |
Price | $370 |
Order / More Info | Mouse CD27 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |