SMAD5 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SMAD5 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.06 mL, 0.12 mL, 0.2 mL |
| Concentration | 1mg/mL |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Bone morphogenetic proteins (BMPs) constitute a large family of signaling molecules that regulate a wide range of critical processes including morphogenesis, cell-fate determination, proliferation, differentiation, and apoptosis (1, 2). BMP receptors are members of the TGF-beta family of Ser/Thr kinase receptors. Ligand binding induces multimerization, autophosphorylation, and activation of these receptors (3-5). They subsequently phosphorylate Smad1 at Ser463 and Ser465 in the carboxy-terminal motif SSXS, as well as Smad5 and Smad8 at their corresponding sites. These phosphorylated Smads dimerize with the coactivating Smad4 and translocate to the nucleus, where they stimulate transcription of target genes (5). MAP kinases and CDKs 8 and 9 |
| Immunogen | Immunogen: Recombinant protein of human SMAD5 Observed Molecular Weight: 52kDa |
| Other Names | [DKFZp781C1895; DKFZp781O1323; Dwfc; JV5-1; MADH5] |
| Gene, Accession # | [SMAD5], Gene ID: 4090, NCBI: AAB66353.1 |
| Catalog # | MBS2526313 |
| Price | $150, $225, $360 |
| Order / More Info | SMAD5 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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