IRF8 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | IRF8 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Plays a role as a transcriptional activator or repressor (PubMed:25122610). Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a negative regulatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3' ), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes. |
| Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 137-426 of human IRF8 (NP 002154.1). |
| Other Names | [ICSBP; IRF-8; ICSBP1; IMD32A; IMD32B; H-ICSBP] |
| Gene, Accession # | [IRF8], Gene ID: 3394, NCBI: NP_002154.1, UniProt: Q02556 |
| Catalog # | MBS8549174 |
| Price | $280 |
| Order / More Info | IRF8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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