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Antigenic Specificity | FcRn-Specific |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FcRn-Specific Antibody detects endogenous levels of FcRn-Specific. Binds to the Fc region of monomeric immunoglobulins gamma (PubMed:7964511, PubMed:10933786). Mediates the selective uptake of IgG from milk and helps newborn animals to acquire passive immunity. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids (By similarity). Possible role in transfer of immunoglobulin G from mother to fetus (PubMed:7964511).Similarity: Belongs to the immunoglobulin superfamily. |
Immunogen | Immunogen: A synthesized peptide derived from human FcRn-Specific. Fragment: Fab fragment |
Other Names | [FcRn - Internal; Alpha chain; Fc fragment of IgG, receptor transporter, alpha; FCGRN_HUMAN; FCGRT; FcRn alpha chain; FcRn; FCRN, alpha chain; IgG Fc fragment receptor transporter alpha chain; IgG Gc receptor; IgG receptor FcRn large subunit p51; IgG receptor FcRn large subunit p51 precursor; Immunoglobulin receptor, intestinal, heavy chain; Neonatal Fc receptor;] |
Gene, Accession # | [FcRn], Gene ID: 2217, NCBI: NP_001129491.1, UniProt: P55899 |
Catalog # | MBS9611359 |
Price | $240, $280 |
Order / More Info | FcRn-Specific Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |