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Antigenic Specificity | IKK Alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IKKalpha is part of a large protein complex responsible for the inducible phosphorylation of IkB proteins. Human IKK-alpha is an 85 kDa peptide that has been shown to activate NFkB by phosphorylation of IkB proteins. IKKalpha interacts with its upstream kinase, NIK, and its downstream substrate, the IkB proteins. Mutations of IKKalpha in its kinase domain lead to a dominant-negative phenotype that suppresses TNF-alpha and IL-1 beta induced NFkB activation. |
Immunogen | Immunogen: IKK alpha was raised in Rabbit using E coli expressed recombinant human IKKa as the immunogen. |
Other Names | [Rabbit IKK alpha; IKK alpha; IKK alpha; TCF16; IKBKA; IKK-A; IKK-1; CHUK; IKKA; IKK1; NFKBIKA; IKKa] |
Gene, Accession # | [IKKA], Gene ID: 1147, UniProt: O15111 |
Catalog # | MBS5311210 |
Price | $430 |
Order / More Info | IKK Alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |