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Antigenic Specificity | Human MAP3K5 / ASK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ASK1 (Ab-83) Antibody detects endogenous levels of total ASK1 protein. MEKK5, also known as ASK1 for apoptosis signal-regulating kinase-1, is a MAP3K type protein kinase and a member of the JNK and p38 MAP kinase signaling pathways. The protein contains a centrally located protein kinase domain, a N-terminal extension that includes binding regions for the Fas-associated adapter protein Daxx and the redox-sensing enzyme thioredoxin, and a C-terminal extension that binds members of the TNFR-associated factor (TRAF) family. |
Immunogen | Immunogen Description: Synthetic peptide from human ASK1 (aa49-98). |
Other Names | [MAP3K5 / ASK1 (aa49-98) IHC-plus; MAP3K5; ASK-1; ASK1; MEKK5; MEK kinase 5; MEKK 5; MAPK/ERK kinase kinase 5; MAPKKK5; MAP/ERK kinase kinase 5; Human MAP3K5; ASK1], [ASK1] |
Gene, Accession # | [MAP3K5], Gene ID: 4217, NCBI: NP_005914.1, UniProt: Q99683 |
Catalog # | MBS243989 |
Price | $530 |
Order / More Info | Human MAP3K5 / ASK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |