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Antigenic Specificity | Claudin 5 (Phospho-Tyr217) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of Claudin 5 only when phosphorylated at tyrosine 217. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome.Sirotkin H., Genomics 42:245-251(1997).Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).The MGC Project Team; Genome Res. 14:2121-2127(2004). |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 217 (K-K-N-Y(p)-V) derived from Human Claudin 5. |
Other Names | [CLD5; CLDN5; TMDVCF] |
Gene, Accession # | Gene ID: 7122, NCBI: NP_001124333.1, UniProt: O00501 |
Catalog # | MBS9400839 |
Price | $200, $255 |
Order / More Info | Claudin 5 (Phospho-Tyr217) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |