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Antigenic Specificity | Synphilin-1 (829-847) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | 1ug/ul |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: A high level of specificity has been shown for this antiserum by IHC on human brain. Synuclein alpha interacting protein (Synphilin-1) contains several protein-protein interaction domains and interacts with alpha synuclein in neurons. Mutations of SNCAIP have been linked to Parkinson disease. The amino acid sequence of synphilin-1 shares a high level of identity with its human counterpart, particularly in regions containing ankyrin-like motifs and the coiled-coil domain. Expression pattern of synphilin-1 in tissues is similar in both mouse and human. Synphilin-1 has an important role in the formation of aggregates and cytotoxicity in Parkinson disease and also Dorfin may be involved in the pathogenic process by ubiquitylation o |
Immunogen | Immunogen: A synthetic peptide (SLELNGEKDKDKGRTLQRT) as part of human synphilin-1a conjugated to KLH has been used as the immunogen. Storage Buffer: PBS, pH 7.4 with 0.02% sodium azide. |
Other Names | [synphilin-1 isoform G; Synphilin-1; synphilin-1; synuclein alpha interacting protein; Alpha-synuclein-interacting protein] |
Gene, Accession # | Gene ID: 9627, NCBI: NP_001295038.1, UniProt: Q9Y6H5 |
Catalog # | MBS4152711 |
Price | $515 |
Order / More Info | Synphilin-1 (829-847) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |