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Antigenic Specificity | MAPK1/3 (Phospho-Tyr205/222) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of MAPK1/3 only when phosphorylated at tyrosine 205/222. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 205/222(K-G-Y(p)-T-K) derived from Human MAPK1/3. |
Other Names | [ERK; ERT1; MAPK 1; MAPK2; ERK2] |
Gene, Accession # | [MAPK1/3], Gene ID: 5594, NCBI: NP_002736.3, UniProt: P28482 |
Catalog # | MBS9410624 |
Price | $200, $255 |
Order / More Info | MAPK1/3 (Phospho-Tyr205/222) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |